Objective: biochemical function

Objective: biochemical function

DNA sequencing enables the discovery of new genes in high-throughput, low-cost experiments. Conversely, gene function is determined by low-throughput, high-cost experiments. This inverse relationship for these two types of data is a major impediment in meeting one of the major scientific challenges of our time—the understanding of genomes. This mismatch in throughput is illustrated by consideri...

An Objective Function for Independence

The problem of separating a linear or nonlinear mixture of independent sources has been the focus of many studies in recent years. It is well known that the classical principal component analysis method, which is based on second order statistics, performs poorly even in the linear case, if the sources do not have Gaussian distributions. Based on this fact, several algorithms take in account hig...

An objective function for STDP

We introduce a weight update formula that is expressed only in terms of firing rates and their derivatives and that results in changes consistent with those associated with spike-timing dependent plasticity (STDP) rules and biological observations, even though the explicit timing of spikes is not needed. The new rule changes a synaptic weight in proportion to the product of the presynaptic firi...

A Novel Objective Function for Directional Overcurrent Relays Coordination

Directional overcurrent relays (DOCRs) are widely used to protect power systems. For optimal coordination of DOCRs, several techniques have been proposed to solve this problem. A common way of optimal coordination of DOCRs is using evolutionary algorithms such as genetic algorithm (GA). In this paper, a novel strategy for DOCRs coordination is proposed. In the proposed strategy, a new objective...

Chloroplast Integrity and Biochemical Function.